Can RDW be normal in iron deficiency anemia?

Normal value for RDW in adults and children is 11.5%- 14.5% and for infants is 15.1-16%. Out of total 100 cases RDW was abnormal in 98% cases. In moderate and severe iron deficiency anemia all cases were having RDW in abnormal range while in mild cases of iron deficiency anemia 91.3% cases had abnormal RDW.

Can you have microcytic anemia with normal hemoglobin?

Normochromic microcytic anemias Normochromic means that your red blood cells have a normal amount of hemoglobin, and the hue of red is not too pale or deep in color.

What is the RDW in microcytic anemia?

Microcytic anemias with an elevated RDW (greater heterogeneity) were used to distinguish iron deficiency from heterozygous thalassemia, which was said to have a normal RDW (more homogeneous).

Is RDW normal in thalassemia?

The RDW is normal in patients with thalassemia and anemia of chronic disease but high in those with iron deficiency. The MCV is decreased in iron-deficiency anemia and in thalassemia minor and normal or decreased in chronic disease.

What causes microcytosis without anemia?

Two gene deletions result in alpha-thalassemia trait, which usually leads to microcytosis without anemia. Hemoglobin electrophoresis is often normal in patients with silent carrier status or with alpha-thalassemia trait. The diagnosis is usually one of exclusion.

Can you have microcytosis without anemia?

Is RDW elevated in thalassemia?

The RBC distribution width (RDW) is elevated (reflecting anisocytosis) in untreated β-thalassemia major, but it is often normal in β-thalassemia minor. On a peripheral blood film, the RBCs are typically microcytic and hypochromic, except in silent carrier phenotypes, in which RBCs appear normal.

Is RDW high or low in thalassemia?

Is microcytic anemia the same as iron deficiency anemia?

Abstract. Microcytic anemia is defined as the presence of small, often hypochromic, red blood cells in a peripheral blood smear and is usually characterized by a low MCV (less than 83 micron 3). Iron deficiency is the most common cause of microcytic anemia.

What lab values indicate microcytic anemia?

Microcytic anemia is a type of anemia where the average erythrocyte is smaller than normal and much smaller than a leukocyte. On the complete blood count (CBC), its measure is under 80 fL while normal MCV is between 80 to 100 fL.

How is microcytic anemia diagnosed?

Microcytic anemia describes a condition in which the red blood cells are small. This can occur due to several causes, including nutritional deficiency, hereditary conditions, acute or chronic bleeding, or chronic disease. Microcytic anemia causes nonspecific symptoms. The diagnosis relies on blood tests.

Is RDW increased in thalassemia?

Until now, many studies have shown a high efficacy of RDW in distinguishing IDA from the thalassemia trait, but this has not been the same for thalassemia disease. Our study used RDW for differentiating between IDA and NTDT in adults with moderate to severe microcytic anemia, according to the WHO classification.

How is RDW normal in thalassemia?

Is RDW high in beta thalassemia?