What is single umbilical artery associated with?

Single umbilical artery (SUA) refers to a variation of umbilical cord anatomy in which there is only one umbilical artery. It may be an isolated finding, or associated with aneuploidy or other congenital anomalies.

Can SUA cause preterm labor?

SUA has been associated with various malformations and pathologies such as cardiac malformations, cleft lip or palate, esophageal atresia, ano-rectal atresia/stenosis (7) and adverse pregnancy outcomes such as preterm birth, diabetes, epilepsy, preeclampsia, polyhydramnios, and oligohydramnios (3).

Can single umbilical artery affect pregnancy?

Having only one artery in the umbilical cord, called a single umbilical artery (SUA), shouldn’t affect their health. Usually, an umbilical cord has two arteries, along with a single vein, making a total of three vessels. The vein carries oxygen and nutrients to your baby, and the arteries remove waste products.

Should I worry about SUA?

Is SUA high risk?

SUA is associated with an increased risk of chromosomal aberrations and congenital malformations in the fetus5, 14-17. These malformations have been reported to occur in most organ systems5, 12, 14-16, but reported findings have not been consistent2, 5, 8, 12, 16, 18, 19.

How often is SUA misdiagnosed?

The sensitivity and specificity of first trimester ultrasound for SUA were 84.2% and 99.8%. The positive predictive value was 84.2% and the negative predictive value was 99.8% with a false negative rate of 15.8% and false positive rate of 0.2%.

What is single umbilical artery?

In Single Umbilical Artery (SUA), there is only one umbilical artery, which affects the blood supply between the mother and the developing fetus. The placenta is an organ that connects the developing fetus to the uterine wall.

What are the outcomes of single umbilical artery disease?

(Outcomes/Resolutions) Single Umbilical Artery can be a life-threatening condition with a high mortality rate. In many cases, it may result in the termination of the pregnancy or a stillbirth After birth of the baby, the baby should be evaluated for heart defects and genetic abnormalities

Is single umbilical artery associated with increased risk of renal anomalies?

Single umbilical artery as compared with double umbilical artery was associated with increased risk of renal anomalies (adjusted odds ratio [OR] 3.0, 95% confidence interval [CI] 1.9-4.9, P<.01) and cardiac anomalies (adjusted OR 20.3, 95% CI 13.5-30.4, P<.01).

What are the signs and symptoms of single umbilical artery?

The signs and symptoms of Single Umbilical Artery may include: Decreased blood flow to the fetus resulting in fetal distress SUA is associated with a variety of birth defects that may be revealed on a prenatal imaging scan How is Single Umbilical Artery Diagnosed? The diagnosis of Single Umbilical Artery may involve: